Splinters of Daoloth

Those who enter the Sacred Light (an avatar of Daoloth) become aware that it is a living, alien presence. At first, the person experiences euphoria, but as the subject’s mind fills with knowledge, terror follows as this knowledge mounts and mounts, becoming too much for their mind to bear. Unless finding some way to stop the process, the acquisition of cosmic truths may turn this person into a Splinter of Daoloth.

Spider Parasites of Atlach-Nacha

 Atlach-Nacha sends out spider-like creatures which can take over the mind of others.

Children of Shub-Niggurath

Children of Shub-Niggurath are grown from a seed pod and are human-shaped bundles of muscle and tentacles, constantly twisting and flexing, with numerous red or yellow eyes and a multitude of small mouths. Their head is simply a great slavering maw.

(Note: I couldn't find an image to accompany this entry, but I personally envision them as human-shaped Dark Young)

Reanimates

Reanimates are an entirely new creation for Call of Cthulhu. Being based off an original Lovecraft story—Re-Animator—I'm surprised their inclusion took this long. For those unfamiliar with the story (or the popular movie), they are basically zombies, created using a chemical reagent concocted by Herbert West. The longer the corpse was originally dead, the more bestial the Reanimate, driving West to always search for fresher and fresher corpses.

Lurkers

Aberrant shapes of twisted flesh and bone. Some are mockeries of humanity, possessing additional limbs or heads, while others might pass for human in dim light. Common to all are fanged teeth in overlarge mouths, used to bite down on their prey and open savage wounds through which they drink the blood of the living.

Blighted Ones

Blighted Ones are humans who have succumbed to a fungal parasite. From the moment of infection, they have mere days before the fungus takes control of their bodies.